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For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
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Internal Ctrl Lentivirus is a transcription factor reporter lentiviral vector designed to monitor the Retinoic acid signaling pathway Retinoid X Receptor signaling signaling pathway in living cells It delivers a Renilla Luc reporter cassette together with a Blasticidin selection marker for generation of stable cell pools The lentiviral vector pseudotyped with VSV-G enables efficient gene delivery and stable genomic integration Typical applications include pathway activity monitoring assay development high content screening and mechanism of action studies It is suitable for use with Human/mouse cells This product is intended for research use only and is not for diagnostic or therapeutic procedures
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Plasmid MaxiPrep Kit, Purification of supercoiled plasmid DNA, 16 samples per kit, Endotoxin level <0.1 EU/μg, Processing time 42 min for 1-2 samples, Elution volume 5 mL
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This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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